Human biochemistry carefully explained
Enzymes, hormones, and signals — written for readers who want the machinery, not the jargon.
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Hormones and signaling
Cold hits the nerves first and the thyroid later
The first response to cold is sympathetic. Thyroid hormone turnover changes on a slower clock than shivering.

Energy metabolism
Lactate is a fuel, not the thing that burns
Working muscle ships lactate as a fuel other tissues can oxidize. The burn is not lactate acting as a toxin.
